I found a way to get debugging back for my Galaxy Nexus while running Eclipse on Windows 8. It was very annoying to go without using ADB for my Galaxy Nexus. I had about 3-4 months where Eclipse ADB would not detect my device. I would turn debugging on and off, reset ADB with kill-server, reinstall device drives, but got nowhere. ... Fortunately, Google searches related to Nexus 7 and ADB got me to a Stack Overflow page that had the information I needed. What I needed was buried in one of the comments: "how to activate USB debugging for the NEW Nexus 7 on Windows 8".